SCUBE3

signal peptide, CUB domain and EGF like domain containing 3

2 disorders 1 biomarker 1 causative 6p21.3 gene with protein product

HGNC:13655 Monarch NCBI Gene 222663 ENSG00000146197 UniProt Q8IX30 OMIM 614708

Previous symbols: CEGF3. Aliases: FLJ34743.

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

Disorder	Relationship	Where the gene appears
Bone Giant Cell Tumor	biomarker
SCUBE3-Related Short Stature Syndrome	causative germline	mechanism: Loss of SCUBE3 BMP Co-Receptor Function

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.