Previous symbols: TUBA1. Aliases: FLJ30169, H2-ALPHA.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Semantic Dementia | susceptibility germline | |
| TUBA4A-related Disorder | causative germline unknown |
mechanism: Altered Alpha-Tubulin 4A (TUBA4A) Function
|
An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.
| ClinGen disease | MOI | Classification | dismech entry |
|---|---|---|---|
| amyotrophic lateral sclerosis type 22 MONDO:0014531 | AD | Moderate 2025-03-27 |
TUBA4A-related Disorder
causative
|
| autosomal dominant macrothrombocytopenia MONDO:0015372 | AD | Limited 2026-02-02 |
no dismech entry |
Identity from HGNC (snapshot 2026-10-24). Page layers are described in the gene pages documentation.