TRDN

triadin

2 disorders 1 causative 1 untyped 6q22.31 gene with protein product

HGNC:12261 Monarch NCBI Gene 10345 ENSG00000186439 UniProt Q13061 OMIM 603283

Aliases: TRISK.

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

Disorder	Relationship	Where the gene appears
Familial Long QT Syndrome	causative	subtype: Type 16 scoped to subtype: Type 16
RYR2 CPVT	untyped Causative	mechanism: Triadin Deficiency subtype: CPVT5

ClinGen gene–disease validity · snapshot 2026-10-03 · matched to entries by MONDO

An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.

ClinGen disease	MOI	Classification	dismech entry
long QT syndrome MONDO:0002442	AR	Strong 2020-04-24	no dismech entry
catecholaminergic polymorphic ventricular tachycardia MONDO:0017990	AR	Definitive 2021-01-20	RYR2 CPVT untyped

Mechanism modules · computed from kb/

cardiac_ion_channel_repolarization via RYR2 CPVT

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.