Previous symbols: PDB2, LOH18CR1. Aliases: RANK, CD265, FEO, ODFR, TRANCE-R.
Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.
| Disorder | Relationship | Where the gene appears |
|---|---|---|
| Adult-Onset Myasthenia Gravis | susceptibility |
scoped to subtype: LOMG
|
| Familial Expansile Osteolysis | causative germline gain of function |
mechanism: TNFRSF11A Exon 1 Signal-Peptide Tandem Duplication
|
| Juvenile Paget Disease | causative germline | |
| Osteopetrosis | causative |
mechanism: Defective osteoclast differentiation (osteoclast-poor forms)
subtype: ARO; ARO7
scoped to subtype: ARO7
|
| Paget Disease of Bone | susceptibility |
mechanism: Osteoclast Precursor Hypersensitivity to RANKL
|
| Aneurysmal Bone Cyst | no genetic record |
mechanism: RANKL-Driven Osteoclast Recruitment
|
Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.