TCF7L2 - dismech genes

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

Disorder	Relationship	Where the gene appears
Gestational Diabetes Mellitus	susceptibility germline
Diabetes mellitus	untyped Risk factor	scoped to subtype: type 2 diabetes mellitus
Type 2 Diabetes Mellitus	untyped Risk Factor	mechanism: Incretin Axis Dysfunction computational model: Topp Beta-Cell Mass / Insulin / Glucose Model

ClinGen gene–disease validity · snapshot 2026-10-03 · matched to entries by MONDO

An entry matches when ClinGen's MONDO disease is the entry's own disease term, a subtype term, or an exact-match mapping. An amber status marks an entry ClinGen supports the gene for (Definitive, Strong or Moderate) whose own record does not type it. A Limited, Disputed or Refuted tier on such an entry is not a gap.

ClinGen disease	MOI	Classification	dismech entry
complex neurodevelopmental disorder MONDO:0100038	AD	Definitive 2021-12-15	no dismech entry

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.