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BCR

BCR activator of RhoGEF and GTPase
2 disorders 1 somatic driver 1 no genetic record 22q11.23 gene with protein product
HGNC:1014MonarchNCBI Gene 613ENSG00000186716UniProt P11274OMIM 151410

Previous symbols: D22S11, BCR1. Aliases: D22S662, CML, PHL, ALL.

In the knowledge base · computed from kb/ at build time

Disorders

Relationship is the entry's genetic[].relationship_type. untyped means the entry has a genetic record for the gene but does not type it; its free-text association is shown instead.

DisorderRelationshipWhere the gene appears
Chronic Myeloid Leukemia, BCR-ABL1 Positive somatic driver somatic gain of function
mechanism: BCR-ABL1 Fusion Oncogene Formation
Mixed Phenotype Acute Leukemia no genetic record
mechanism: BCR-ABL1 Kinase-Driven Proliferative Signaling
Mechanism modules · computed from kb/

Identity from HGNC (snapshot 2026-10-01). Page layers are described in the gene pages documentation.