This resource is in its pre-alpha development stage. Content is actively being curated and may be incomplete or subject to change.

Cystic echinococcosis

Infectious Disease MONDO:0018408 Helminth infection Neglected tropical disease

Cystic echinococcosis is a helminthic disease caused by the larval stage of Echinococcus granulosus.

0
Mappings
0
Definitions
0
Inheritance
1
Pathophysiology
0
Histopathology
1
Phenotypes
0
Genes
2
Treatments
0
Subtypes
0
Differentials
0
Datasets
0
Trials
⚙

Pathophysiology

1
Hepatic cyst formation
Larval cysts commonly develop in the liver.
Show evidence (1 reference)
PMID:27047771 SUPPORT
"Upon infection with CE, cyst formation mainly occurs in the liver (70%)."
The abstract reports predominant liver cyst formation.
●

Phenotypes

1
Hepatic cysts COMMON Hepatic HP:0001407
Show evidence (1 reference)
PMID:27047771 SUPPORT
"Upon infection with CE, cyst formation mainly occurs in the liver (70%)."
The abstract indicates liver cyst formation is common.
💊

Treatments

2
Benzimidazole chemotherapy MAXO:0000058
Benzimidazole carbamates are used as chemotherapy.
Show evidence (1 reference)
PMID:27047771 SUPPORT
"Treatment methods include chemotherapy with benzimidazole carbamates and/or surgical approaches, including percutaneous aspiration injection and reaspiration."
The abstract lists benzimidazole chemotherapy among treatments.
Surgical and percutaneous approaches MAXO:0000004
Surgical approaches including percutaneous aspiration are used.
Show evidence (1 reference)
PMID:27047771 SUPPORT
"Treatment methods include chemotherapy with benzimidazole carbamates and/or surgical approaches, including percutaneous aspiration injection and reaspiration."
The abstract lists surgical and percutaneous approaches.
{ }

Source YAML

click to show 
name: Cystic echinococcosis
creation_date: '2026-01-26T15:56:41Z'
updated_date: '2026-01-26T15:56:41Z'
category: Infectious Disease
description: >-
  Cystic echinococcosis is a helminthic disease caused by the larval stage of
  Echinococcus granulosus.
disease_term:
  term:
    id: MONDO:0018408
    label: cystic echinococcosis
  preferred_term: Cystic echinococcosis
parents:
- Helminth infection
- Neglected tropical disease
infectious_agent:
- name: Echinococcus granulosus
  infectious_agent_term:
    preferred_term: Echinococcus granulosus
    term:
      id: NCBITaxon:6210
      label: Echinococcus granulosus
  description: Tapeworm whose larval stage causes cystic echinococcosis.
  evidence:
  - reference: PMID:27047771
    supports: SUPPORT
    snippet: "Cystic echinococcosis (CE) is a widely endemic helminthic disease caused by infection with metacestodes (larval stage) of the Echinococcus granulosus tapeworm."
    explanation: The abstract identifies E. granulosus metacestodes as the cause of CE.
transmission:
- name: Dog-associated egg transmission
  description: Tapeworm eggs from dogs and other canids can infect humans.
  evidence:
  - reference: PMID:40944955
    supports: SUPPORT
    snippet: "Dogs and other canids harboring gut-resident tapeworms readily transmit the tapeworm eggs (and subsequent formation of larval cysts) to humans in close contact with them."
    explanation: The abstract describes transmission of eggs from dogs and other canids to humans.
pathophysiology:
- name: Hepatic cyst formation
  description: Larval cysts commonly develop in the liver.
  evidence:
  - reference: PMID:27047771
    supports: SUPPORT
    snippet: "Upon infection with CE, cyst formation mainly occurs in the liver (70%)."
    explanation: The abstract reports predominant liver cyst formation.
phenotypes:
- name: Hepatic cysts
  category: Hepatic
  frequency: COMMON
  phenotype_term:
    preferred_term: Hepatic cysts
    term:
      id: HP:0001407
      label: Hepatic cysts
  evidence:
  - reference: PMID:27047771
    supports: SUPPORT
    snippet: "Upon infection with CE, cyst formation mainly occurs in the liver (70%)."
    explanation: The abstract indicates liver cyst formation is common.
treatments:
- name: Benzimidazole chemotherapy
  description: Benzimidazole carbamates are used as chemotherapy.
  treatment_term:
    preferred_term: pharmacotherapy
    term:
      id: MAXO:0000058
      label: pharmacotherapy
  evidence:
  - reference: PMID:27047771
    supports: SUPPORT
    snippet: "Treatment methods include chemotherapy with benzimidazole carbamates and/or surgical approaches, including percutaneous aspiration injection and reaspiration."
    explanation: The abstract lists benzimidazole chemotherapy among treatments.
- name: Surgical and percutaneous approaches
  description: Surgical approaches including percutaneous aspiration are used.
  treatment_term:
    preferred_term: surgical procedure
    term:
      id: MAXO:0000004
      label: surgical procedure
  evidence:
  - reference: PMID:27047771
    supports: SUPPORT
    snippet: "Treatment methods include chemotherapy with benzimidazole carbamates and/or surgical approaches, including percutaneous aspiration injection and reaspiration."
    explanation: The abstract lists surgical and percutaneous approaches.