Class: UpstreamConditionHypothesis

Hypothesized upstream condition that may explain both A and B.

URI: dismech:UpstreamConditionHypothesis

 classDiagram
    class UpstreamConditionHypothesis
    click UpstreamConditionHypothesis href "../UpstreamConditionHypothesis/"
      UpstreamConditionHypothesis : description

      UpstreamConditionHypothesis : evidence





        UpstreamConditionHypothesis --> "*" EvidenceItem : evidence
        click EvidenceItem href "../EvidenceItem/"



      UpstreamConditionHypothesis : upstream_disorder





        UpstreamConditionHypothesis --> "0..1" ConditionDescriptor : upstream_disorder
        click ConditionDescriptor href "../ConditionDescriptor/"

Slots

Name	Cardinality and Range	Description	Inheritance
upstream_disorder	0..1 ConditionDescriptor	Upstream disorder referenced in a hypothesis	direct
description	0..1 String		direct
evidence	* recommended EvidenceItem		direct

Usages

used by	used in	type	used
ComorbidityAssociation	shared_upstream_hypotheses	range	UpstreamConditionHypothesis

Identifier and Mapping Information

Schema Source

• from schema: https://w3id.org/monarch-initiative/dismech

Mappings

Mapping Type	Mapped Value
self	dismech:UpstreamConditionHypothesis
native	dismech:UpstreamConditionHypothesis

LinkML Source

Direct

name: UpstreamConditionHypothesis
description: Hypothesized upstream condition that may explain both A and B.
from_schema: https://w3id.org/monarch-initiative/dismech
slots:
- upstream_disorder
- description
- evidence

Induced

name: UpstreamConditionHypothesis
description: Hypothesized upstream condition that may explain both A and B.
from_schema: https://w3id.org/monarch-initiative/dismech
attributes:
  upstream_disorder:
    name: upstream_disorder
    description: Upstream disorder referenced in a hypothesis
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: upstream_disorder
    owner: UpstreamConditionHypothesis
    domain_of:
    - UpstreamConditionHypothesis
    range: ConditionDescriptor
    inlined: true
  description:
    name: description
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: description
    owner: UpstreamConditionHypothesis
    domain_of:
    - Descriptor
    - GeneticContext
    - Dataset
    - ClinicalTrial
    - ComputationalModel
    - DifferentialDiagnosis
    - Subtype
    - CausalEdge
    - TreatmentMechanismTarget
    - EpidemiologyInfo
    - Pathophysiology
    - Phenotype
    - HistopathologyFinding
    - Environmental
    - Disease
    - Stage
    - AgentLifeCycle
    - AgentLifeCycleStage
    - AnimalModel
    - Treatment
    - InfectiousAgent
    - Transmission
    - Assay
    - Diagnosis
    - Inheritance
    - Variant
    - FunctionalEffect
    - Mechanism
    - ModelingConsideration
    - Definition
    - CriteriaSet
    - ConditionDescriptor
    - GOEnrichment
    - ComorbidityHypothesis
    - UpstreamConditionHypothesis
    - MechanisticHypothesis
    range: string
  evidence:
    name: evidence
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: evidence
    owner: UpstreamConditionHypothesis
    domain_of:
    - PhenotypeContext
    - Dataset
    - ClinicalTrial
    - ComputationalModel
    - DifferentialDiagnosis
    - Subtype
    - CausalEdge
    - TreatmentMechanismTarget
    - Finding
    - Prevalence
    - ProgressionInfo
    - EpidemiologyInfo
    - Pathophysiology
    - Phenotype
    - Biochemical
    - HistopathologyFinding
    - Genetic
    - Environmental
    - Stage
    - AgentLifeCycle
    - AgentLifeCycleStage
    - AnimalModel
    - Treatment
    - InfectiousAgent
    - Transmission
    - Diagnosis
    - Inheritance
    - Variant
    - ModelingConsideration
    - ClassificationAssignment
    - Definition
    - CriteriaSet
    - AssociationSignal
    - AssociationStatistics
    - ComorbidityHypothesis
    - UpstreamConditionHypothesis
    - MechanisticHypothesis
    range: EvidenceItem
    recommended: true
    multivalued: true
    inlined: true
    inlined_as_list: true