Enum: TreatmentEffectEnum

How a treatment affects a pathophysiology mechanism node

Permissible Values

Value	Meaning	Description
INHIBITS	None	Blocks or decreases the mechanism (e
ACTIVATES	None	Promotes or increases the mechanism (e
MODULATES	None	Alters the mechanism without clear unidirectional effect
BYPASSES	None	Works around the disrupted mechanism via an alternative pathway
RESTORES	None	Restores normal function of a disrupted mechanism (e

Slots

Name	Description
treatment_effect	How the treatment affects the targeted mechanism

Identifier and Mapping Information

Schema Source

from schema: https://w3id.org/monarch-initiative/dismech

LinkML Source

name: TreatmentEffectEnum
description: How a treatment affects a pathophysiology mechanism node
from_schema: https://w3id.org/monarch-initiative/dismech
rank: 1000
permissible_values:
  INHIBITS:
    text: INHIBITS
    description: Blocks or decreases the mechanism (e.g., TKI inhibiting constitutive
      kinase activity)
  ACTIVATES:
    text: ACTIVATES
    description: Promotes or increases the mechanism (e.g., enzyme replacement restoring
      a deficient pathway)
  MODULATES:
    text: MODULATES
    description: Alters the mechanism without clear unidirectional effect
  BYPASSES:
    text: BYPASSES
    description: Works around the disrupted mechanism via an alternative pathway
  RESTORES:
    text: RESTORES
    description: Restores normal function of a disrupted mechanism (e.g., gene therapy,
      enzyme replacement)