Class: ComorbidityHypothesis

Mechanistic hypothesis for a comorbidity association, with rich text and embedded evidence plus atomic pathophysiology elements.

URI: dismech:ComorbidityHypothesis

 classDiagram
    class ComorbidityHypothesis
    click ComorbidityHypothesis href "../ComorbidityHypothesis/"
      ComorbidityHypothesis : description

      ComorbidityHypothesis : evidence





        ComorbidityHypothesis --> "*" EvidenceItem : evidence
        click EvidenceItem href "../EvidenceItem/"



      ComorbidityHypothesis : pathophysiology





        ComorbidityHypothesis --> "*" Pathophysiology : pathophysiology
        click Pathophysiology href "../Pathophysiology/"

Slots

Name	Cardinality and Range	Inheritance
description	0..1 String	direct
evidence	* recommended EvidenceItem	direct
pathophysiology	* Pathophysiology	direct

Usages

used by	used in	type	used
ComorbidityAssociation	hypotheses	range	ComorbidityHypothesis

Identifier and Mapping Information

Schema Source

from schema: https://w3id.org/monarch-initiative/dismech

Mappings

Mapping Type	Mapped Value
self	dismech:ComorbidityHypothesis
native	dismech:ComorbidityHypothesis

LinkML Source

Direct

name: ComorbidityHypothesis
description: Mechanistic hypothesis for a comorbidity association, with rich text
  and embedded evidence plus atomic pathophysiology elements.
from_schema: https://w3id.org/monarch-initiative/dismech
slots:
- description
- evidence
- pathophysiology

Induced

name: ComorbidityHypothesis
description: Mechanistic hypothesis for a comorbidity association, with rich text
  and embedded evidence plus atomic pathophysiology elements.
from_schema: https://w3id.org/monarch-initiative/dismech
attributes:
  description:
    name: description
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: description
    owner: ComorbidityHypothesis
    domain_of:
    - Descriptor
    - GeneticContext
    - Dataset
    - ClinicalTrial
    - ComputationalModel
    - DifferentialDiagnosis
    - Subtype
    - CausalEdge
    - TreatmentMechanismTarget
    - EpidemiologyInfo
    - Pathophysiology
    - Phenotype
    - HistopathologyFinding
    - Environmental
    - Disease
    - Stage
    - AgentLifeCycle
    - AgentLifeCycleStage
    - AnimalModel
    - Treatment
    - InfectiousAgent
    - Transmission
    - Assay
    - Diagnosis
    - Inheritance
    - Variant
    - FunctionalEffect
    - Mechanism
    - ModelingConsideration
    - Definition
    - CriteriaSet
    - ConditionDescriptor
    - GOEnrichment
    - ComorbidityHypothesis
    - UpstreamConditionHypothesis
    - MechanisticHypothesis
    range: string
  evidence:
    name: evidence
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: evidence
    owner: ComorbidityHypothesis
    domain_of:
    - PhenotypeContext
    - Dataset
    - ClinicalTrial
    - ComputationalModel
    - DifferentialDiagnosis
    - Subtype
    - CausalEdge
    - TreatmentMechanismTarget
    - Finding
    - Prevalence
    - ProgressionInfo
    - EpidemiologyInfo
    - Pathophysiology
    - Phenotype
    - Biochemical
    - HistopathologyFinding
    - Genetic
    - Environmental
    - Stage
    - AgentLifeCycle
    - AgentLifeCycleStage
    - AnimalModel
    - Treatment
    - InfectiousAgent
    - Transmission
    - Diagnosis
    - Inheritance
    - Variant
    - ModelingConsideration
    - ClassificationAssignment
    - Definition
    - CriteriaSet
    - AssociationSignal
    - AssociationStatistics
    - ComorbidityHypothesis
    - UpstreamConditionHypothesis
    - MechanisticHypothesis
    range: EvidenceItem
    recommended: true
    multivalued: true
    inlined: true
    inlined_as_list: true
  pathophysiology:
    name: pathophysiology
    from_schema: https://w3id.org/monarch-initiative/dismech
    rank: 1000
    alias: pathophysiology
    owner: ComorbidityHypothesis
    domain_of:
    - Disease
    - Stage
    - ComorbidityHypothesis
    range: Pathophysiology
    multivalued: true
    inlined: true
    inlined_as_list: true