DISMECH Capability Metrics

Aggregate QA/QC metrics showing DISMECH coverage, evidence depth, ontology grounding, mechanistic modeling, and treatment coverage.

Generated: 2026-10-04 20:22 UTC

Curated Entries

3,300

Disorder YAML files analyzed

Evidence Items

228,943

Cited evidence blocks

Ontology Terms

148,879

Grounded descriptor terms

Pathophysiology Nodes

23,140

Mechanism events

Causal Edges

46,196

Downstream mechanism links

Avg Weighted Compliance

90.1

From linkml-data-qc reports

MONDO Exact Pages

3,215

Human-disease descendants with exact DISMECH pages

MONDO Exact + Parent

11,277

Terms represented by exact or ancestor pages

Evidence Quality

Unique evidence references
46,198
Average evidence items per entry
69.4
Evidence SourceItems
HUMAN_CLINICAL149,937
OTHER31,666
IN_VITRO19,883
MODEL_ORGANISM18,945
UNSPECIFIED7,443
COMPUTATIONAL1,069

Ontology Richness

Entries with HPO phenotype terms
100.0%
Average HPO terms per entry
12.8
Average GO terms per entry, all sections
6.8
Average CL terms per entry, all sections
4.1
Ontology PrefixTerms
HP50,797
GO22,275
NCIT20,303
HGNC17,800
CL13,631
MONDO8,775
UBERON5,910
CHEBI5,751
NCBITAXON2,684
ECTO588
RO113
ICD10CM72
XCO56
LOINC23
ENVO22
FOODON22
OPL22
ICD11F20
MGI9
OBI5
PR1

Mechanistic Depth

Average pathophysiology nodes per entry
7.0
Average causal edges per entry
14.0
Entries using mechanism modules
38.4%
Module-conforming nodes
3,441

Treatment Coverage

Total treatments
14,094
Entries with treatments
95.5%
Total clinical trials
1,575
Entries with clinical trials
20.5%

Curation Velocity

MonthCreatedUpdated
2026-10291
2026-0969121
2026-087943
2026-073091
2026-063570
2026-053210
2026-042690
2026-03990
2026-021270
2026-011560
2025-121270
2025-06190

Disorder Page Section Coverage

Section Entries Entry Coverage Total Items Average Items / Entry
Phenotypes3,299100.0%42,64212.9
Pathophysiology3,29699.9%23,1407.0
Treatments3,15395.5%14,0944.3
Genetics2,86286.7%7,3142.2
Diagnostics2,38872.4%5,9791.8
Inheritance2,21367.1%2,5270.8
Prevalence2,17866.0%3,0240.9
Classifications1,50945.7%2,1160.6
Differential Diagnoses1,34840.8%4,1251.2
Animal Models1,16835.4%2,3200.7
Progression1,16035.2%2,5820.8
Biochemical Markers1,06032.1%2,7250.8
Datasets68820.8%1,9010.6
Clinical Trials67720.5%1,5750.5
Environmental Factors60718.4%1,3110.4
Experimental Models57417.4%1,1940.4
Histopathology55716.9%1,0420.3
Definitions3049.2%3880.1
Epidemiology2066.2%4100.1
Transmission1685.1%2980.1
Computational Models461.4%990.0
Stages411.2%1160.0

MONDO Coverage

MONDO scope
human disease (MONDO:0700096) descendants
Total MONDO terms in scope
23,237
Exact DISMECH pages
3,215
Represented by parent disorder page
8,062
Represented only by child disorder page
1,848
Exact or parent-page representation
48.5%
Any page relation
56.5%

Parent-page representation counts a MONDO disease term when DISMECH has a page for one of its ancestor disorders. Direct MONDO human-disease classes can overlap because MONDO terms may descend from more than one class.

Human Disease Class Coverage

MONDO Class ID Terms Exact Pages Parent Pages Child Only Exact + Parent
acute diseaseMONDO:002068340444243971.0%
disease by developmental or physiological processMONDO:77700077,2981,3932,68649755.9%
disease by etiologic mechanismMONDO:777000817,8012,7807,1451,13255.8%
disease by body system or componentMONDO:777000618,8262,5797,6231,27454.2%