> **Evidence retrieval unavailable: cited report cannot be produced**
>
> No retrievable papers, clinical trials, or patents were returned in this run, and OpenTargets queries failed after retries.
>
> Because no source documents produced any citable context IDs, a PMID-cited report with verified URLs, publication dates, abstract quotes, and evidence-grounded disease claims cannot be generated in this session.
>
> Minimum inputs needed for a successful follow-up run:
> - PMIDs for key EDN3/EDNRB Waardenburg–Shah papers
> - DOI links to relevant articles
> - PDFs of primary papers or reviews
> - OMIM disease or gene entries
> - Orphanet disease page(s)
> - GeneReviews chapter or link


*Blockquote: This notice explains that no retrievable evidence sources were available in the session, preventing a PMID-cited report. It also lists the minimum source inputs needed to enable a fully referenced follow-up run.*